MINING METAGENOMES AND METATRANSCRIPTOMES UNVEILS VIRUSES ASSOCIATED WITH CUTANEOUS SQUAMOUS CELL CARCINOMA IN HEMATOPOIETIC STEM CELL TRANSPLANT RECIPIENTS

ABSTRACT We investigated the presence of viral DNA and RNA in cutaneous squamous cell carcinoma (cSCC) tumor and normal tissues from nine individuals with a history of hematopoietic stem cell transplantation (HCT).Microbiome quantification through DNA and RNA sequencing (RNA-seq) revealed the presence of 18 viruses in both tumor and normal tissues.

The Eurasian fossil record of Panthera spelaea shows a gradual decrease in body size.The Oven Frame Repair Kit process peaking just before the extinction of the species at the end of the Late Pleistocene.The temporal trend of decreasing size particularly accelerating during MIS 2, as exemplified by the extremely small female skull from Kryshtaleva

A series of divalent and one trivalent metal chelates of the azo ligand resulting from coupling of sulfafurazole diazonium chloride with resorcinol have been designed and synthesized.Structure investigation of the isolated chelates have been achieved by applying spectroscopic and analytical tools which collaborated to assure the formation of Table